Coagulation, also known as clotting, is the transformation of blood from a liquid to a gel, resulting in the formation of a blood clot. It could lead to hemostasis or the halt of blood loss from a damaged vessel and then repair.
Coagulation is caused by platelet activation, adhesion, and aggregation, as well as fibrin deposition and maturation. The coagulation mechanism includes platelet activation, adhesion, and aggregation, as well as fibrin deposition and maturation.
A Coagulation Analyzer is a device that quickly and easily tests blood samples for an individual’s blood clotting characteristics and measures blood platelet levels. A coagulation analyzer can detect the speed of the coagulation pathway, as well as the levels of thrombin and thromboplastin, in as short as a few minutes.
Working of Coagulation Analyzer
Photo-optical detection technology is the most advanced coagulation analyzer or coagulometer technology available today. As a result, coagulometers or coagulation analyzers that use photo-optical detection principles should be the best choice for a laboratory.
The coagulation test is used to calculate factors like specific proteins in the blood that cause a clot to form. The PT and aPTT are the two most common coagulation screening tests. This is based on two distinct coagulation pathways: intrinsic (measured by an aPTT test) and extrinsic (PT test to measure).
The tests must be conducted within four hours of receiving the sample to obtain accurate results. It requires the collection of a plasma sample in sodium citrate tubes. Since this material is not stable for a long period, tests must be performed as soon as possible after it is obtained.
During coagulation testing, the PT and aPTT tests are conducted simultaneously to check for bleeding issues or the likelihood of significant bleeding during an upcoming surgery. This test is routinely performed at a hospital before surgery to assess for liver disease and clotting problems.
In laboratories, this test is utilized as an anticoagulant treatment. The ideal aPTT and PT times are 25–40 seconds for aPTT and 11–16 seconds for PT, respectively.
Features of Coagulation Analyzer
- Lower reagent volume (e.g., 50ul for PT) minimises cost per test, allowing patients to benefit from lower charges.
- LED technology is favoured over traditional halogen lamps since it extends the life of the device.
- User-friendly touch screen interface.
- In recollection, there are at least 100 patient results.
- The results are available in INR, Ratio, and Percentage.
Agappe’s Coagulation Analyzers
Agappe is a well-known diagnostics company specialising in clinical chemistry reagents and instruments research, design, and manufacturing. It is one of the greatest in their area, founded in 1995.
Agappe’s coagulation analyzers, which work on the turbo densitometric measuring principle, are among the finest coagulation analyzers available in the market. The device offers an automated result computation based on seconds, INR, per cent, g/L, mg/dL, and the ratio, with single and duplicate measurement options.
It provides cutting-edge technology solutions, including seven pre-programmed test positions and nine calibration points. It also contains one reagent incubation position and four sample incubation positions, making it one of the top coagulation analyzers on the market.
